Pair Name	Toosendanin, Camptothecin
Disease Info	[ICD-11: 2C77]	Cervical cancer		Investigative
Biological Phenomena	Induction-->Autophagy
Gene Regulation	Down-regulation	Activity	ATP6AP2	hsa10159
	Down-regulation	Expression	CTSB	hsa1508
	Down-regulation	Expression	CTSD	hsa1509
	Up-regulation	Expression	SQSTM1	hsa8878
In Vitro Model	HeLa	Human papillomavirus-related cervical adenocarcinoma	Homo sapiens (Human)	CVCL_0030
	A-549	Lung adenocarcinoma	Homo sapiens (Human)	CVCL_0023
In Vivo Model	1×10⁶ HeLa cells stably expressing mRFP-GFP-LC3 were suspended in 100 μL serum-free culture medium and inoculated into the left axilla.
Result	These results suggest that toosendanin has the potential to be developed into an anti-cancer drug by blocking chemotherapy-induced protective autophagy.